CASY-MSCCN Jobs

Job Description

The Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) function of our Research & Development Division in West Point, Pennsylvania, is seeking a highly skilled and motivated Scientist to join the Transporter Science Group. The Transporter Science group is a center of excellence to design, execute, and integrate transporter related in vitro and preclinical studies to support our Company's Portfolio through all stages of drug discovery and development. We are also driving cutting edge ADME-transporter science via development and implementation of novel in vitro and preclinical models, as well as translational approaches to enhance our capabilities to quantitatively predict the roles of transporters on ADME, drug-drug interactions (DDIs), efficacy, and toxicity of drugs in a diversified portfolio that spans various therapeutic areas and modalities.

In this position, candidates will be responsible to generate transporter related in vitro data to support discovery and development programs. Candidates will also have the opportunity to work closely with other scientists across the network to advance our scientific strategy via developing and implementing novel tools/emerging technologies. Successful candidates should have a passion for generating high quality data for use by project teams across a range of therapeutic areas and must be able to work independently with a range of in vitro assay systems and have the capability to contribute to complex research projects to address project related issues. In addition, candidates will be conducting experiments using automated liquid handlers and other sophisticated scientific instrumentation. Candidates must have excellent written and verbal communications and experience working in a team environment.

Position Qualifications :

Education Minimum Requirement:

• A master’s degree in a relevant field or bachelor’s degree in a relevant field (e.g. Pharmaceutical Sciences, Biochemistry, Biology, Molecular and Cell Biology, Pharmacology, and Biotechnology) with 3+ years of relevant laboratory experience

Required Experience and Skills:

• Cell culture, including aseptic techniques and maintenance of recombinant cell lines and primary cells

• Demonstrated ability to design, perform and interpret in vitro studies generated in cell lines, hepatocytes or subcellular fractions

• Ability to work independently and effectively to develop and validate new assays with some technical and strategic supervision

• Proficiency in data handling software such as Excel and Graphpad, ability to document results accurately and generate reports to be shared with internal partners or regulatory agencies

• Strong communication and collaboration skills with flexibility to operate in a team environment

• Autonomy, attention to details, critical thinking, self-driven, and growth mindset

Preferred Experience and Skills:

• Experience with assay automation and operation of liquid handlers

• Experience and /or knowledge with transporter and enzyme related studies in drug discovery and development

• Experience in designing, conducting, and interpretating various in vitro transporter phenotyping, inhibition and kinetic studies

• Basic understanding of quantitation using radiometric or LC/MS methods

• Experience working in the pharmaceutical industry or contract research organizations

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

11/13/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R319245